Pharmacogenomics Test

What your results look like

Your report sorts every medication into one of three categories. Usual prescribing considerations means your genetics aren't expected to affect that drug, and it's prescribed normally. Minor means an altered response is possible but the evidence is limited or the effect small, so monitoring is the recommendation rather than a dose change. Major means a significant effect is predicted, and there is published guidance to consider a different dose, closer monitoring, or an alternative drug. A small number carry a flag recommending an alternative outright — for example, someone who forms very little of clopidogrel's active metabolite gets reduced antiplatelet protection, which is the kind of finding that changes a cardiologist's choice.

Alongside that you get your genotype and predicted phenotype for each of the nine genes, the reasoning behind every recommendation, and the guideline it comes from. Two things to be clear about. This report is prescribing information for your doctor, not instructions for you — never stop, start or change a dose of anything based on it. And a "major" flag doesn't mean a medication is off-limits: if a drug is already working well and you're tolerating it, that usually outweighs what the genotype predicts. Genetics is one input among several, and drug interactions, kidney and liver function, age and other medications all still apply.