Understand Your Immune System & Autoimmunity
Your immune system plays a central role in inflammation, energy, recovery, gut health, allergies and long-term disease risk. Whether you’re dealing with recurring infections, unexplained symptoms, autoimmune concerns, or allergic reactions, our immune system tests help uncover what’s driving your symptoms. From allergy testing and autoimmune blood tests to cytokine panels, viral screening and inflammation markers like the CRP blood test, these assessments give you a clear, science-based understanding of your immune health. For a broader perspective on immune function, read our article on why immune balance matters more than immune boosting.
How i-screen works
01Order online
Choose your preferred blood test and place your order securely through our website.
02Receive pathology request form
We'll email you your pathology request form, which you'll need for your blood draw.
03Visit a Collection Centre
Take your pathology request form to one of our affiliated collection centres for your blood sample.
04Get your results
Your results are typically available within 48 hours depending on the test. We'll notify you by email when your results are ready to view in your i-screen dashboard.
Choose your focus
Jump straight to the area that best matches your goal or symptoms
Want the most complete picture of your immune and autoimmune health?
Our comprehensive immune panels analyse immune activation, regulation, inflammation, allergy pathways and autoimmune markers. These tests help identify whether your symptoms are driven by overactivity, underactivity or hidden immune dysregulation.
Measure ANA and key autoimmune markers — results to discuss with your GP if autoimmune concerns are relevant.
Measure NK cell count and lymphocyte subsets to assess immune function, viral defence and fertility-related immunity.
Advanced 16-cytokine panel measuring immune signalling molecules linked to chronic inflammation and inflammaging.
Screen 27 vitamins and minerals including zinc, selenium, magnesium, B vitamins and antioxidants in one panel.
Is your immune system overreactive or underperforming?
Your immune system can become overactive, contributing to autoimmune symptoms, or underactive, increasing susceptibility to infections and chronic inflammation. Autoimmune markers like HLA-B27 and HLA-DQ/DR haplotypes, alongside NK cell, cytokine and broader autoimmune testing, can reveal immune dysregulation and genetic risk factors that may be driving your symptoms.
Measure NK cell count and lymphocyte subsets to assess immune function, viral defence and fertility-related immunity.
Advanced 16-cytokine panel measuring immune signalling molecules linked to chronic inflammation and inflammaging.
Measure ANA and key autoimmune markers — results to discuss with your GP if autoimmune concerns are relevant.
Measure HLA-B27 — a genetic marker relevant to certain autoimmune conditions. Discuss results with your GP.
Genetic test for predisposition to coeliac disease, type 1 diabetes, rheumatoid arthritis and autoimmune thyroid.
Do chronic or reactivated viral infections affect your health?
Viruses such as EBV, CMV, Lyme disease and Ross River can stay dormant in the body and reactivate during periods of stress, leading to fatigue, joint pain, immune dysfunction and ongoing inflammation. Viral testing identifies past infection, recent exposure or reactivation so you can better understand whether persistent symptoms are linked to immune-viral interactions.
Blood test for EBV antibodies to confirm current or past Epstein-Barr virus infection (mono/glandular fever).
Cytomegalovirus is a common infection with a wide range of symptoms - from no symptoms to fever and fatigue, to severe symptoms involving the eyes, brain, or other internal organs.
Measure Borrelia burgdorferi antibodies — relevant for those with a history of tick exposure. Discuss results with your GP.
Lyme disease is a tick-borne infection caused by the bacteria Borrelia burgdorferi. The first symptom is usually a characteristic pink or red rash that starts as a small red spot that gradually spreads in a much larger circle.
Test for Ross River virus antibodies - Australia’s most common mosquito-borne infection causing joint pain and fatigue.
Could food sensitivities or gut issues be triggering immune symptoms?
Food reactions, allergies and gut-immune interactions can drive inflammation, digestive symptoms, fatigue, eczema, sinus issues and autoimmune flare-ups. Our allergy and food sensitivity panel, including allergy blood tests, food allergy testing and gluten testing, can help identify triggers and uncover underlying immune drivers.
Measure coeliac antibody markers. Coeliac disease affects approximately 1 in 70 Australians. Discuss results with your GP.
Test for HLA-DQ2 and HLA-DQ8 gene variants — markers relevant to coeliac disease susceptibility.
A food intolerance occurs when someone has difficulty digesting a particular food - this can lead to symptoms such as intestinal gas, abdominal pain or diarrhoea. This Food Intolerance Check includes a screen for 96 foods.
A food intolerance occurs when someone has difficulty digesting a particular food - this can lead to symptoms such as intestinal gas, abdominal pain or diarrhoea. This Food Intolerance Test includes an IgG screen for 96 common foods.
Allergies are on the increase, and food allergies in particular are becoming more common. Measure IgE antibodies across 27 common food and environmental allergens. These allergens may be from foods, pollens, house dust, animal hair or moulds.
Advanced DNA-based PCR gut test measuring bacteria, pathogens, parasites, viruses and inflammation markers.
Is chronic inflammation a hidden factor?
Chronic low-grade inflammation can drive fatigue, joint pain, cardiovascular risk and accelerated ageing — often without obvious symptoms. CRP, cytokine panels and homocysteine testing can detect this invisible inflammation. Read our deep dive into inflammaging: the slow-burning inflammation that accelerates ageing to understand why managing inflammation is one of the most important steps you can take for long-term health.
Simple blood test for C-reactive protein (CRP) — a widely used marker of inflammation.
Measure homocysteine levels — a biomarker commonly included in cardiovascular and wellness assessments.
Advanced 16-cytokine panel measuring immune signalling molecules linked to chronic inflammation and inflammaging.