Autoimmune disorders run in families and are caused when the body's immune system begins to attack healthy tissue - this causes inflammation and damage. Symptoms are known as particular branches of autoimmune disease, such as thyroiditis (Hashimoto’s or Graves’ Disease), lupus, diabetes, rheumatoid arthritis and coeliac disease for example. Several symptoms can be associated which means an individual's family members could be diagnosed with different symptoms of autoimmune disease.

Characteristics of autoimmune disorders may include chronic, progressive arthritic symptoms, fever, fatigue, muscle weakness, and/or a rash that can not readily be explained.

What we test

Autoantibodies Test

Autoantibodies may attack the body’s own cells causing signs and symptoms such as tissue and organ inflammation, joint and muscle pain, and fatigue.

This blood test measures

The antinuclear antibody (ANA) test is a marker of the autoimmune process that is positive with a variety of autoimmune diseases.

Rheumatoid factor is a type of autoantibody which is often elevated in inflammation, for example inflammation associated with rheumatoid arthritis.


C-reactive protein is often the first evidence of inflammation or an infection in the body. Its concentration increases in the blood within a few hours after the start of infection or other inflammatory injury. ESR measures the degree of inflammation present in the body.

This blood test measures:

C-reactive protein (CRP) is a protein that increases due to inflammation. There is growing evidence that atherosclerosis (fatty build-up in artery walls) is an inflammatory process, however this type of inflammation produces only small amounts of CRP. Therefore this test is known as high-sensitivity CRP or hs-CRP.

ESR is an indirect measure of the degree of inflammation present in the body. Increased blood levels of certain proteins (such as fibrinogen or immunoglobulins, which are increased in inflammation) increase the ESR.

Test instructions

Print out the pathology form that we email you.

Take your form to your local collection centre to have your blood sample taken - no need for an appointment.

You do not need to fast for this blood test.

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