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S-Adenosylmethionine (SAMe), derived from methionine, is a universal methyl donor involved in methylation reactions. These reactions are crucial for DNA synthesis, mental health, and detoxification. SAMe also supports joint health, cancer management and mood regulation, making it a valuable compound for managing conditions like depression, osteoarthritis, and liver disease. SAMe levels reflect the body’s ability to methylate, and testing SAMe can help identify potential methylation deficiencies or imbalances.

S-Adenosylhomocysteine (SAH) is a precursor to homocysteine and a byproduct of SAMe-dependent methylation reactions. Elevated SAH levels can indicate impaired methylation efficiency, potentially contributing to various health issues, including cardiovascular disease and neurological conditions.

What we test

SAMe and SAH

Monitoring SAMe and SAH levels can provide insights into methylation status and guide interventions to support optimal health.

This blood test measures:

SAMe is a universal methyl donor involved in methylation reactions. These reactions are crucial for DNA synthesis, mental health, and detoxification.

SAH is a precursor to homocysteine and a byproduct of SAMe-dependent methylation reactions. Elevated SAH levels can indicate impaired methylation efficiency.

The SAM/SAH ratio reflects the balance between methylation reactions in the body, and can provide insights into cellular health, metabolism, and disease processes.

Test instructions

You’ll receive your blood test kit in the mail, along with logistics for your sample collection. Prepaid postage and packaging is included.

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