Precision Cardiovascular Blueprint

A Coronary Calcium Score test is a fast, non-invasive CT scan that measures the amount of calcium build-up in the arteries of your heart - the earliest physical sign of coronary artery disease. This calcium, or plaque, can indicate the presence of coronary artery disease (CAD) long before symptoms like chest pain appear.

This assessment combines an electrocardiogram (ECG) with advanced cardiac biomarkers to provide a clear, early view of how well your heart is functioning. The ECG measures your heart’s electrical activity to evaluate rhythm, rate and conduction patterns, helping detect hidden arrhythmias or early signs of cardiac stress. High-sensitivity troponin and NT-proBNP offer deeper insight into heart muscle health by detecting subtle cell injury, strain or increased workload long before symptoms appear. Together, these tests reveal early changes in cardiac function, allowing for timely, targeted prevention and long-term heart health optimisation.

Atherosclerosis begins silently, driven by oxidative stress, inflammation, and genetic factors that influence how your blood vessels respond to damage. This panel combines advanced blood biomarkers (hsCRP, homocysteine, and oxidised LDL) with key genetic variants (PON1, NOS3, and MTHFR) to assess vascular health at the molecular level. Together, these markers reveal early arterial inflammation, plaque activity, oxidative stress, and impaired endothelial repair, providing powerful insight into your cardiovascular risk and guiding targeted, proactive prevention strategies.

Metabolic health plays a critical role in cardiovascular risk, and insulin resistance often develops silently, driving inflammation, weight changes, and arterial plaque formation long before diabetes appears. This panel combines genetic insights (TCF7L2, a key gene influencing insulin sensitivity and glucose regulation) with advanced metabolic blood markers including fasting glucose, insulin, HbA1c, triglycerides, HOMA-IR and the TyG index. Together, they reveal how effectively your body manages blood sugar and energy. Identifying early metabolic imbalance enables targeted nutrition, exercise and lifestyle strategies that help restore metabolic efficiency and reduce long-term cardiovascular risk.

Cholesterol and lipids play a central role in cardiovascular health, influencing how fats are transported, used, and stored in the body. While some cholesterol is essential, elevated or poorly balanced levels can accumulate in artery walls and drive plaque formation. This panel combines ApoE genetic insights, which influence how efficiently you clear and metabolise cholesterol, with detailed blood lipid markers including total cholesterol, LDL, VLDL, HDL, triglycerides and non-HDL cholesterol. Together, they provide a precise picture of your lipid metabolism and inherited risk, helping you understand how lifestyle, diet and genetics interact to shape your long-term heart health.

Lipoproteins provide a deeper understanding of cardiovascular risk by measuring not just cholesterol levels, but how cholesterol is transported throughout the body. ApoA1 reflects protective HDL particles, while ApoB represents the atherogenic particles that contribute to plaque formation—making the ApoB/ApoA1 ratio one of the most precise indicators of cardiovascular risk. This panel also includes Lipoprotein(a), a powerful, genetically determined risk marker influenced by your LPA genotype, which can elevate heart disease risk even when other lipids are normal. Together, these genetic and blood-based markers reveal both inherited and functional lipid risk, enabling personalised prevention strategies.

Your lipid subfraction profile looks beyond total cholesterol to assess the size and density of LDL particles, offering a clearer view of cardiovascular risk. Larger, more buoyant LDL particles (LDL-1 and LDL-2) are generally protective, while smaller, denser particles (LDL-3 to LDL-7) are more likely to penetrate artery walls and promote plaque formation. By analysing the balance between these subfractions and your mean LDL particle size, this test provides a precise indication of how your cholesterol behaves — revealing whether your lipid profile supports heart health or signals a higher risk of atherosclerosis.

The Precision Cardiovascular Screen includes a teleconsult with an experienced specialist to interpret your results, discuss personal risk factors, and develop a targeted action plan for prevention and optimisation.