Methylation Pathways Test
$375 AUD
This test is designed as a follow up to the Genetic Methylation Check. The Methylation Pathways Check is a urine test that analyses key metabolic markers to reveal how your body manages nutrients, energy, and detoxification. Paired with the Genetic Methylation Check, this test provides a comprehensive view of your current metabolic health.
Genetic methylation testing provides valuable insights into your body’s potential by identifying variations in key genes that influence methylation. But genes are only part of the picture — they reveal your blueprint, but not necessarily how your body is functioning in real time.
The Methylation Pathways Check measures compounds in your urine which reflect the effectiveness of critical processes in your body. By analysing these metabolites or methylation pathways, you'll gain insights into your body's:
- Cellular energy production
- Detoxification efficiency
- Neurotransmitter balance
- Oxidative stress and antioxidant capacity
- Vitamin and nutrient status
- Gut health (bacterial or yeast overgrowth)
What's included
Nutrient & Vitamin Status
This area combines two different views of your nutrient status: "functional" markers that rise when your body is working harder to use a vitamin, and direct measurements of vitamins passing through in urine. Together they give a rough indication of which nutrients may be in higher demand, though a blood test is still the gold standard for confirming any specific deficiency.
This urine test measures:
Neurotransmitter Activity
After your body uses brain chemicals like dopamine, serotonin, and adrenaline, it breaks them down into smaller by-products that pass out in urine, which this area measures as an indirect read on messenger activity. These markers are influenced by diet, sleep, stress, caffeine and medications, so a single reading is rarely diagnostic on its own.
This urine test measures:
Oxidative Stress & Detoxification
This area looks at how well your body is handling everyday cellular wear-and-tear and clearing the substances your liver needs to process — medications, hormones, alcohol, and the by-products of your own metabolism. Temporary elevations are common after intense exercise, illness, or high alcohol intake, and are usually not concerning in isolation.
This urine test measures:
Environmental Exposure Markers
These markers look for traces of industrial solvents — particularly xylene, found in paints, glues, printing inks, and cigarette smoke — that leave distinctive chemical fingerprints when your body processes them. A raised reading here usually points first to smoking status, then to work, hobbies, or recent contact with solvent-containing products.
This urine test measures:
Gut & Microbial Balance
This area looks at chemicals produced by the trillions of microbes living in your gut, giving a rough read on which microbial groups are more or less active than usual. It won't tell you exactly which species are present, but it can flag patterns worth a closer look with your clinician.
This urine test measures:
Oxalate Metabolites
Oxalates are naturally occurring substances in foods like spinach and almonds, however, when your gut flora is out of balance, excess oxalates are absorbed, which can cause joint pain, urinary discomfort, skin rashes, fatigue, or brain fog.
This urine test measures:
B-Complex Vitamins & Amino Acid Markers
Your B-vitamins contribute to almost every metabolic process. These markers help detect where additional B1, B2, B3, B5, B6, or biotin may be needed to aid with symptoms like fatigue or hormonal imbalance.
This urine test measures:
Citric Acid Cycle Metabolites
The citric acid (Krebs) cycle is the method by which your body turns food into cellular energy (ATP). Issues here typically cause low energy, brain fog, and intolerance to exercise.
This urine test measures:
Energy Production
Your cells turn food into energy through a series of chemical steps inside the mitochondria, and this area measures the by-products of those steps to see how smoothly the process is running. Isolated findings here are common and often shift with diet or recent activity — the pattern across markers matters more than any single result.
This urine test measures:
Ketone/ Fatty Acid Metabolites
When your body uses fat as fuel, it produces certain metabolites. High levels of Adipic Acid, Suberic Acid, or Ethylmalonic Acid may point to issues with fat metabolism, which is often due to carnitine or riboflavin (B2) deficiencies.
This urine test measures:
Test instructions
You’ll receive your urine test kit in the mail, along with logistics for your sample collection.
Results for this test typically available in 2-3 weeks and will be published in your online dashboard.
Ready. Set. Go!
for $375