Precision Gut Blueprint

The Precision Gut Blueprint is a practitioner-facing clinical summary tool that organises laboratory results into a visual dashboard format to support, not replace, professional clinical interpretation and decision-making. It does not diagnose, treat, or predict any condition; all findings require review and contextualisation by a qualified healthcare practitioner before any clinical action is taken.

Genetics play an essential role in shaping your gut health, influencing everything from how you feed beneficial bacteria to how you tolerate foods and respond to inflammation. This panel includes key variants such as FUT2 (secretor status affecting microbiome diversity), HLA-DQ2.5/DQ8 (coeliac predisposition), DAO (histamine breakdown), MTHFR (methylation and inflammatory balance), and TLR4 (immune response to gut microbes). Together, these markers provide a deeper understanding of your digestive function and your gut’s unique vulnerabilities, helping you interpret your microbiome results with greater precision and guiding more personalised nutrition and lifestyle strategies.

Hydrogen and methane measured in parts per million at baseline, then at 30, 60, 90, 120, 150 and 180 minutes. Lactulose travels further along the small intestine than glucose, so it can pick up overgrowth lower down. Methane at about 10 ppm or above at any point is generally treated as positive; methane is produced by archaea rather than bacteria, and that pattern is termed intestinal methanogen overgrowth (IMO).

The Food Intolerance Check assesses your response to 96 foods. Your blood is screened for IgG antibodies to these foods using the ELISA method. Your results also come with a suggested Personal Rotation Diet Guideline designed to reduce food sensitivities, enhance nutrient diversity, and support gut health. This involves rotating different food groups every 3-4 days to minimise immune system reactivity, prevent overexposure to specific allergens, and promote a diverse gut microbiome.

Gut functional markers assess how well the gut is performing its key roles in digestion, absorption, and immune defence. They measure important indicators such as enzyme activity, inflammation levels, gut barrier function, and detoxification capacity. Together, these markers provide a clearer picture of overall digestive system health.

This urine test assesses levels of a synthetic sugar and mannitol that can be used to monitor improvements or deterioration in intestinal permeability.

People with coeliac disease who eat gluten have higher than normal levels of tissue transglutaminase antibodies in their blood. These antibodies are produced by the immune system because it views gluten - the proteins found in wheat, rye and barley - as a threat. This test is positive in about 98% of patients with coeliac disease who are on a gluten-containing diet. Note that a negative result does not necessarily exclude coeliac disease, and if you are symptomatic you may require further testing. A biopsy of the small intestine is the only way to formally diagnose coeliac disease.

If the intestines can't absorb nutrients then they are eliminated from the body in the stool. This can happen when there's damage to the intestine, as well as the amount of time available where nutrients can be absorbed from food as it passes through the gut.

Short-chain fatty acids are what your gut bacteria make when they ferment dietary fibre. Butyrate is the one to watch — it's the primary fuel source for the cells lining your colon, and low levels are a common finding when the community is depleted. This stool test reports all four: butyrate, acetate, propionate and valerate. Most panels report three or none.

Diversity is measured two ways here. The Shannon and Simpson indices score how many different species are present and how evenly they're distributed — a community dominated by a few organisms scores lower than a balanced one, even with the same species count. Alongside those sits your Firmicutes-to-Bacteroidetes ratio and your distribution across the six major phyla. These are the numbers worth recording, because they're what a retest in six months compares against.

Research has identified microbiome patterns that appear more often in people with certain gut-related conditions. This section shows how your community compares against those published patterns. This is a research comparison — not a genetic test, a risk score or a diagnosis. A pattern resembling one described in the literature doesn't mean you have or will develop that condition. It's context for a conversation with a practitioner.

Because sequencing reads genes rather than only identifying organisms, GutIQ can report what your microbiome is equipped to do — its capacity to produce compounds such as lipopolysaccharides, histamine, trimethylamine, branched-chain amino acids and indolepropionic acid, and how it handles carbohydrate, lipid and protein metabolism. This is the layer neither culture-based nor targeted-PCR testing can reach.

Pathogenic bacteria are harmful microbes that can cause acute infections, inflammation, and disrupt the gut microbiome. Detecting these bacteria early helps prevent serious illness and supports faster recovery. Managing pathogenic infections is essential for maintaining a healthy and resilient digestive system.

Yeast and fungi naturally exist in small amounts within the gut but can cause health problems if they grow unchecked. Overgrowth may lead to digestive discomfort, skin issues, fatigue, and weakened immunity. Assessing fungal balance helps identify hidden drivers of gut symptoms and supports targeted recovery.

This panel detects H. pylori by both antigen testing and quantitative PCR, so you get a measured level rather than a yes/no. It identifies eight virulence factors indicating how aggressive a strain is, and checks mutations associated with antibiotic resistance.

Parasites can be present without obvious symptoms and can affect digestion, nutrient absorption and the gut lining. This panel screens for seven of the most common. If one is found, take the result to your doctor — some require medical management, and some are notifiable.

Intestinal worms can cause a range of digestive and immune issues, particularly if left undetected. Identifying and addressing worm infections helps restore proper nutrient absorption and gut balance. Screening for worms is an important step in protecting overall digestive health.

Certain viruses can infect the gastrointestinal tract and contribute to inflammation, digestive symptoms, and immune system strain. Identifying viral infections supports a clearer understanding of gut health and helps guide appropriate immune support strategies. Early detection can help minimise long-term effects on gut function.

A healthy gut microbiome is rich in beneficial bacteria that aid digestion, produce important nutrients, and support immune function. Measuring the levels and balance of these bacteria helps assess the resilience and health of the gut ecosystem. Strong levels of beneficial flora are linked to better digestion, mood balance, and disease prevention.

Opportunistic bacteria are strains that are normally harmless in small amounts but can cause problems if they overgrow. Elevated levels may contribute to digestive symptoms, inflammation, or disruptions in the gut microbiome balance. Monitoring these bacteria helps protect gut health and prevent chronic issues.

Proteins, fats, and carbohydrates are broken down by stomach acids, enzymes produced by the pancreas, and bile from the liver. This process also releases micronutrients. This blood test measures the levels of enzymes produced by the pancreas.

Your liver processes drugs and alcohol, filters toxic chemicals, stores vitamins and minerals, and makes bile, proteins and enzymes. This liver function test measures key liver enzymes and markers relevant to understanding your liver health.

Your kidneys filter waste from your body and regulate salts in your blood. They also produce hormones and vitamins that direct cell activities in many organs and help to control blood pressure.

The gut health consult is a 45-minute session with a qualified dietitian, conducted via a virtual meeting platform. During the session, our dietitian will take a holistic approach by reviewing and considering all your health test results collectively to provide a comprehensive understanding of your gut health picture.